What is the nurses priority assessment for a client receiving enoxaparin?
These groups of drugs affect clot formation and resolution by hindering different steps in clotting formation which include altering the formation of platelet plug (antiplatelet drugs), interfering the clotting cascade and thrombin formation (anticoagulant drugs), and stimulating the plasmin system to break down the formed clot (thrombolytic agents). Show
Coagulation Drugs: Generic and Brand NamesHere is a table of commonly encountered antiplatelet, anticoagulant, and thrombolytic agents, their generic names, and brand names:
Disease Spotlight: Thromboembolic and Hemorrhagic DisordersDisorders that directly affect coagulation process are divided into two main categories: 1) thromboembolic disorders, which involve overproduction of clots; and 2) hemorrhagic disorders, which is characterized by ineffective clotting process leading to excessive bleeding. Thromboembolic disorders include medical conditions (e.g. CAD) which involve overproduction of clots which result into decreased blood flow and total vessel occlusion. Manifestations include hypoxia, anoxia, and even necrosis. These disorders are treated by drugs that interfere with normal coagulation process to prevent formation of clots. On the other hand, less common hemorrhagic disorders is characterized by excessive bleeding. These are treated by drugs that promote the clotting process. Some of these conditions include:
Antiplatelet Agents
Therapeutic Action
Indications
Children
Adults
Pregnant women
Older adults
Pharmacokinetics
Contraindications and Cautions
Adverse Effects
Interactions
Nursing ConsiderationsHere are important nursing considerations when administering antiplatelet agents: Nursing AssessmentThese are the important things the nurse should include in conducting assessment, history taking, and examination:
Nursing DiagnosesHere are some of the nursing diagnoses that can be formulated in the use of this drug for therapy:
Implementation with RationaleThese are vital nursing interventions done in patients who are taking antiplatelet agents:
EvaluationHere are aspects of care that should be evaluated to determine effectiveness of drug therapy:
Anticoagulants
Therapeutic Action
Indications
Children
Adults
Pregnant women
Older adults
Pharmacokinetics
Contraindications and Cautions
Adverse Effects
Interactions
Nursing ConsiderationsHere are important nursing considerations when administering anticoagulants: Nursing AssessmentThese are the important things the nurse should include in conducting assessment, history taking, and examination:
Nursing DiagnosesHere are some of the nursing diagnoses that can be formulated in the use of this drug for therapy:
Implementation with RationaleThese are vital nursing interventions done in patients who are taking anticoagulants:
EvaluationHere are aspects of care that should be evaluated to determine effectiveness of drug therapy:
Thrombolytic Agents
Therapeutic Action
Indications
Children
Adults
Pregnant women
Older adults
Pharmacokinetics
Contraindications and Cautions
Adverse Effects
Interactions
Nursing ConsiderationsHere are important nursing considerations when administering thrombolytics: Nursing AssessmentThese are the important things the nurse should include in conducting assessment, history taking, and examination:
Nursing DiagnosesHere are some of the nursing diagnoses that can be formulated in the use of this drug for therapy:
Implementation with RationaleThese are vital nursing interventions done in patients who are taking thrombolytics:
EvaluationHere are aspects of care that should be evaluated to determine effectiveness of drug therapy:
Practice Quiz: Drugs Affecting CoagulationQuiz time! Take our 3-item quiz about drugs affecting coagulation. 1. Which organ(s) produce(s) clotting factors? A. Bone marrow 2. What is the first reaction to a blood vessel injury? A. Vasodilation and swelling 3. Which of the following substances will alert the nurse for an increased risk of bleeding in a patient taking clopidogrel? A. Chamomile tea Answers and Rationale 1. Answer: C. Liver. The liver produces a cascade of clotting factors that contributes to the process of coagulation by breaking down fibrinogen into insoluble fibrin threads. 2. Answer: B. Vasoconstriction. This is especially helpful for very small injuries to the blood vessel because vasoconstriction can seal off any break and allow the area to heal. 3. Answer: A. Chamomile tea. Increased bleeding with no other cause or link found should lead to the possibility of herbal interactions with drugs. Other herbal sources that can increase the risk of bleeding in patients taking anticoagulants include psyllium, turmeric, garlic, ginkgo, chestnut seed, and goldenseal. Recommended ResourcesRecommended resources and reference books. Disclosure: Includes Amazon affiliate links.
See AlsoHere are other nursing pharmacology study guides:
Gastrointestinal System Drugs
Respiratory System Drugs
Endocrine System Drugs
Autonomic Nervous System Drugs
Immune System Drugs
Chemotherapeutic Agents
Reproductive System Drugs
Nervous System Drugs
Cardiovascular System Drugs
References and SourcesReferences and sources for this pharmacology guide for drugs affecting coagulation:
What should I monitor before giving enoxaparin?Check the patient's most recent lab results, including her complete blood cell and platelet count. Check her medication administration record for previous dose and site. Perform hand hygiene. Prepare the medication and identify the patient according to your facility's guidelines.
What is the nurses priority assessment for a patient receiving heparin treatment?Rationale: When caring for a client who is receiving heparin, the nurse should monitor the aPTT to evaluate medication effectiveness. The aPTT evaluates the intrinsic and final common pathways of the coagulation cascade that are affected by heparin.
What are some nursing considerations for a patient taking anticoagulants?Patients on anticoagulant therapy must be educated about their increased risk for bleeding, monitoring for bleeding, managing bleeding if it occurs, and drug-specific information.
What are precautions for administration of enoxaparin?Stay away from rough sports or other situations where you could be bruised, cut, or injured. Brush and floss your teeth gently. Be careful when using sharp objects, including razors and fingernail clippers. Enoxaparin may cause bleeding problems.
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