What term is used to describe the volume of air that can be expired forcefully after a normal expiration?

Definition of expiratory reserve volume

Ask a medical professional for a definition of expiratory reserve volume (ERV) and they’ll offer something along the lines of: “The extra volume of air that can be expired from the lungs with determined effort following a normal tidal volume expiration.”

Let’s make that easier to understand.

Picture yourself sitting normally and breathing as you do when you are not exerting yourself orexercising. The amount of air you breathe in is your tidal volume.

After you breathe out, try to exhale more until you are unable to breathe out any more air. The amount of air you can force out after a normal breath (think about blowing up a balloon) is your expiratory reserve volume.

You can tap into this reserve volume when you exercise and your tidal volume increases.

To sum up: Your expiratory reserve volume is the amount of extra air — above anormal breath — exhaled during a forceful breath out.

The average ERV volume is about 1100 mL in males and 800 mL in females.

Respiratory volumes are the amount of air inhaled, exhaled, and stored in your lungs. Along with expiratory reserve volume, some terms that are often part of a ventilatory pulmonary function test and can be helpful to know include:

  • Tidal volume. The amount of air you typically breathe into yourlungs when at rest and not exerting yourself. The average tidal volume is about 500 mL for both men and women.
  • Inspiratory reserve volume. The amount of extra air inhaled — above tidal volume — during a forceful breath in. When you exercise, you have a reserve volume to tap into as your tidal volume increases. The average inspiratory reserve volume is about 3000 mL in males and 2100 mL in females.
  • Vital capacity. The total usable volume of the lungs that you can control. This is not the entire lung volume as it is impossible to voluntarily breathe all of the air out of your lungs. The average vital capacity volume is about 4600 mL in males and 3400 mL in females.
  • Total lung capacity. The total volume of your lungs: your vital capacity plus the amount of air you cannot voluntarily exhale. The average total lung capacity volume is about 5800 mL in males and 4300 mL in females.

The amount of lung capacity varies from person to person based on their physical makeup and their environment.

You are likely to have a larger volume if you:

  • are tall
  • live at a higher altitude
  • are physically fit

You are likely to have a smaller volume if you:

  • are short
  • live at alower altitude
  • are obese

Your expiratory reserve volume is the amount of extra air — above-normal volume — exhaled during a forceful breath out.

Measured with spirometry, your ERV is part of the data gathered in pulmonary function tests used to diagnose restrictive pulmonary diseases and obstructive lung diseases.

The following terms describe the various lung (respiratory) volumes:

  • The tidal volume (TV), about 500 mL, is the amount of air inspired during normal, relaxed breathing.
  • The inspiratory reserve volume (IRV), about 3,100 mL, is the additional air that can be forcibly inhaled after the inspiration of a normal tidal volume.
  • The expiratory reserve volume (ERV), about 1,200 mL, is the additional air that can be forcibly exhaled after the expiration of a normal tidal volume.
  • Residual volume (RV), about 1,200 mL, is the volume of air still remaining in the lungs after the expiratory reserve volume is exhaled.

Summing specific lung volumes produces the following lung capacities:

  • The total lung capacity (TLC), about 6,000 mL, is the maximum amount of air that can fill the lungs (TLC = TV + IRV + ERV + RV).
  • The vital capacity (VC), about 4,800 mL, is the total amount of air that can be expired after fully inhaling (VC = TV + IRV + ERV = approximately 80 percent TLC). The value varies according to age and body size.
  • The inspiratory capacity (IC), about 3,600 mL, is the maximum amount of air that can be inspired (IC = TV + IRV).
  • The functional residual capacity (FRC), about 2,400 mL, is the amount of air remaining in the lungs after a normal expiration (FRC = RV + ERV).

Some of the air in the lungs does not participate in gas exchange. Such air is located in the anatomical dead space within bronchi and bronchioles—that is, outside the alveoli.

Definitions

Volume Description Average Notes
Tidal volume Volume that enters and leaves with each breath, from a normal quiet inspiration to a normal quiet expiration 0.5L

Changes with pattern of breathing e.g. shallow breaths vs deep breaths

Increased in pregnancy

Inspiratory reserve volume Extra volume that can be inspired above tidal volume, from normal quiet inspiration to maximum inspiration 2.5L Relies on muscle strength, lung compliance (elastic recoil) and a normal starting point (end of tidal volume)
Expiratory reserve volume Extra volume that can be expired below tidal volume, from normal quiet expiration to maximum expiration 1.5L

Relies on muscle strength and low airway resistance

Reduced in pregnancy, obesity, severe obstruction or proximal (of trachea/bronchi obstruction)

Residual volume/reserve volume Volume remaining after maximum expiration 1.5L Cannot be measured by spirometry


Capacities
are composites of 2 or more lung volumes. They are fixed as they do not change with the pattern of breathing.

Capacity Description Expression Average Notes
Vital capacity/forced vital capacity Volume that can be exhaled after maximum inspiration (to maximum expiration) Inspiratory reserve volume + tidal volume + expiratory reserve volume 4.5L

Often changes in disease

Requires adequate compliance, muscle strength and low airway resistance

Inspiratory capacity Volume breathed in from quiet expiration to maximum inspiration Tidal volume + inspiratory reserve volume 3L
Functional residual capacity Volume remaining after quiet expiration Expiratory reserve volume + residual volume 3L Affected by height, gender, posture, changes in lung compliance. Height has the greatest influence.
Total lung capacity Volume of air in lungs after maximum inspiration Sum of all volumes 6L

Restriction < 80% predicted

Hyperinflation > 120% predicted

Measured with helium dilution

Anatomical (serial) dead space is the volume of air that never reaches alveoli and so never participates in respiration. It includes volume in upper and lower respiratory tract up to and including the terminal bronchioles

Alveolar (distributive) dead space is the volume of air that reaches alveoli but never participates in respiration. This can reflect alveoli that are ventilated but not perfused, for example secondary to a pulmonary embolus.

By OpenStax College [CC BY 3.0 (http://creativecommons.org/licenses/by/3.0)], via Wikimedia Commons

What term is used to describe the volume of air that can be expired forcefully after a normal expiration?

Fig 1 – Diagram showing various lung volumes.

Measuring Volumes and Capacities

Simple Spirometry

Simple spirometry can measure tidal volume, inspiratory reserve volume and expiratory reserve volume. However, it cannot measure residual volume.

Measured values are standardised for height, age and sex, although height is the factor with the greatest influence upon capacities.

Process

The subject breathes from a closed circuit over water. The chamber is filled with oxygen and as they breathe, gas increased and reduces the volumes within the circuit. A weight above the chamber changes height with each ventilation according to the circuit volume. Its height is recorded with a pen to reflect the volume inspired or expired over time.

British Lung Foundation

What term is used to describe the volume of air that can be expired forcefully after a normal expiration?

Fig 2 – Simple spirometry

Helium dilution

Helium dilution is used to measure total lung capacity. However, it is only accurate if the lungs are not obstructed. If there is a point of obstruction, helium may not reach all areas of the lung during a ventilation, producing an underestimate as only ventilated lung volumes are measured.

Process

After quiet expiration, the subject breathes in a gas with a known concentration of helium (an inert gas). They hold their breath for 10 seconds, allowing helium to mix with air in the lungs, diluting the concentration of helium. The concentration of helium is then measured after expiration. The volume of air which is ventilated is then calculated according to the degree of dilution of the helium.

Nitrogen washout

A method for calculating serial/anatomical dead space in the conducting airways up to and including the terminal bronchioles (usually 150mL).

Process

The subject takes a breath of pure oxygen and then exhales through a valve which measures nitrogen levels. At first, pure oxygen is exhaled, representing the dead space volume as the air exhaled never reached the alveoli and underwent gaseous exchange.

Then, a mixture of dead space air and alveolar air is expired, meaning the detected concentration of nitrogen increases as nitrogen rich air from the dead space reaches the valve. After a few breaths, the lungs are washed out of pure oxygen, meaning that purely alveolar air is expired, with the nitrogen levels reflecting that of alveolar air. The levels of nitrogen measured over time can be used to calculate the anatomical dead space volume of the lungs.

Visualising lung volumes

Vitalograph

A vitalograph creates plots of volume against time, using data collected from spirometry tests.

Two important spirometry volumes that can be measured from a Vitalograph are:

  • FVC (forced vital capacity)  – the maximal volume of air that a subject can expel in one maximal expiration from a point of maximal inspiration.
  • FEV1 (forced expiratory volume in one second) – the maximal volume of air that a subject can expel in one second from a point of maximal inspiration.

The proportion of air that can be exhaled in the first second compared to the total volume of air that can be exhaled is important in assessing for possible airway obstruction. This proportion is known as the FEV1/FVC ratio. This ratio is important in clinically for diagnosis of respiratory conditions.

By National Heart Lung and Blood Insitute (NIH) (National Heart Lung and Blood Insitute (NIH)) [Public domain], via Wikimedia Commons

What term is used to describe the volume of air that can be expired forcefully after a normal expiration?

Fig 3 – Image showing the process of spirometry using a spirometer.

Flow volume loop

This plots flow over volume (showing expiratory flow and inspiratory flow as positive and negative values respectively).

Important factors to consider when assessing flow-volume curves are as follows:

  • Peak Expiratory Flow Rate (PEFR) – the rate of flow.
  • Vital capacity – the volume expired, calculated from the X-axis.
  • Shape of the curve – ‘spooning’ in obstructive disease, small overall loop in restrictive disease.

By Evgenios Metaxas MD MSc, Pulmonologist Ευγένιος Μεταξάς MD MSc, Πνευμονολόγος [CC BY-SA 3.0 (http://creativecommons.org/licenses/by-sa/3.0)], via Wikimedia Commons

What term is used to describe the volume of air that can be expired forcefully after a normal expiration?

Fig 4 – A flow-volume loop

Nitrogen washout graph

This plots the percentage concentration of nitrogen in exhaled air (%N) against the total volume of air expired.

The anatomical dead space is determined by the volume of exhaled air at which the volume below the washout curve (A1) is equal to the volume above the washout curve (A2).

Boston University School of Medicine

What term is used to describe the volume of air that can be expired forcefully after a normal expiration?

Figure 5 – A nitrogen washout curve

Clinical relevance – Obstructive and Restrictive Deficits

Process FEV1 FVC FEV1/FVC
Obstructive <80% of predicted Reduced, but not to same degree as FEV1 <0.7
Restrictive <80% of predicted <80% of predicted >=0.7

In obstructive disease, the FEV1 is reduced due to increased resistance during expiration. Air trapping can also occur where more air is inspired than is expired, which can cause the residual volume to increase. In asthma, the obstruction is reversible which can aid in diagnosis. This means that FEV1/FVC will recover on re-test after the application of a bronchodilator such as salbutamol.

The so-called ‘spooning‘ of a flow-volume curve in obstructive disease arises when the affected small airways begin to collapse.

As air exits the thorax in expiration, the pressure within the small airways reduces and thus the small airways are no longer propped open. This increases resistance to expiration and therefore reduces flow.

Examples of obstructive diseases are asthma, COPD (chronic bronchitis, emphysema), tracheal stenosis and large airway tumours.

By User:Evgenios Metaxas MD MSc, Pulmonologist Ευγένιος Μεταξάς MD MSc, Πνευμονολόγος [CC BY-SA 3.0 (http://creativecommons.org/licenses/by-sa/3.0)], via Wikimedia Commons

What term is used to describe the volume of air that can be expired forcefully after a normal expiration?

Fig 6 – Spirometry of a patient with asthma, an obstructive disorder.

In restrictive disease, the FVC is reduced due to poor lung expansion. This can be neurological, due to weak inspiratory muscles or due to an anatomical deformity. This causes the inspiratory reserve volume to be reduced as the lungs can’t inflate as much during maximum inspiration. Residual volume can also be reduced as expiration is more effective than inspiration.

Examples of restrictive diseases are interstitial pulmonary fibrosis, muscle weakness, kyphoscoliosis, obesity, tense ascites.

What is the term for the volume of expired air at forced expiration?

Forced expiratory volume (FEV) measures how much air a person can exhale during a forced breath. The amount of air exhaled may be measured during the first (FEV1), second (FEV2), and/or third seconds (FEV3) of the forced breath. Forced vital capacity (FVC) is the total amount of air exhaled during the FEV test.

What is the term that describes the amount of air a person can inhale forcefully after normal tidal volume inspiration?

The inspiratory reserve volume is the amount of air a person can inhale forcefully after normal tidal volume inspiration; the expiratory reserve volume is the amount of air a person can exhale forcefully after a normal exhalation.

What is the name of the total volume of air that can be forcibly expired after a complete and full inspiration?

Total Lung Capacity The vital capacity (VC) is the maximal volume of gas exhaled during a forced exhalation after a forced inhalation. Thus VC is the sum of the VT, IRV, and ERV. The VC is approximately 4.5 L in a healthy 70-kg adult.

Which of these terms is used to describe the volume of air inspired or expired during the process of normal respiration?

The volume of air inspired or expired during normal respiration is called tidal volume. The average human has a tidal volume of approximately 500cm3.