Respiratory distress is a contraindication for the use of barbiturates.
ADVERTISEMENTS Show
Anxiolytic-hypnotics agents are used to alter an individual’s responses to environmental stimuli. These agents are referred to as anxiolytics (prevent feelings of tension or fear), sedatives (help patient feel calm and unaware of their environment), and hypnotics (help patients sleep).
Brand Names and Generic NamesHere is a table of commonly encountered diuretic agents, their generic names, and brand names: ClassificationsGeneric NameBrand NameBenzodiazepines used as Anxiolytic-HypnoticsalprazolamXanaxchlordiazepoxideLibriumclonazepamKlonopindiazepamValiumlorazepamAtivanoxazepamSeraxtriazolamHalcionBarbiturates used as Anxiolytic-HypnoticsamobarbitalAmytal sodiumbutabarbitalButisolpentobarbitalNembutalphenobarbitalLuminalOther Anxiolytic-Hypnotic Drugsbuspirone diphenhydramineBenadrylmeprobamateMiltownpromethazinePhenerganzolpidemAmbienManifestation Spotlight: Anxiety, Sedation, and HypnosisAnxiety is described as a feeling of tension, nervousness, and apprehension which typically involves unpleasant reactions to a stimulus both real and imaginary. It is accompanied by sympathetic nervous system reactions like fast heartbeat, rapid breathing, flushing, and sweating. Anxiety can be mild, moderate, or severe. Sedation is the loss of awareness and reaction to environmental stimuli. However, this may be desirable for restless and irritable patients. This is also beneficial for patients who are about to undergo surgery. Hypnosis is the further depression and sleep of the central nervous system (CNS) which usually results from extreme sedation. In this state, the person no longer senses or reacts to incoming stimuli. Benzodiazepines Used as Anxiolytic-Hypnotics
Therapeutic Action
Indications
Children
Adults
Older adults
PharmacokineticsRouteOnsetPeakDurationOral30-60 min1-2 h3 hIM15-30 min30-45 min3 hIV1-5 min30 min15-60 minRectalRapid1.5 h3 hT1/2: 20-80 hMetabolism: liver Excretion: urine Contraindications and Cautions
Adverse Effects
Interactions
Nursing ConsiderationsHere are important nursing considerations when administering this drug: Nursing AssessmentThese are the important things the nurse should include in conducting assessment, history taking, and examination:
Nursing DiagnosesHere are some of the nursing diagnoses that can be formulated in the use of this drug for therapy:
Implementation with RationaleThese are vital nursing interventions done in patients who are taking anxiolytic-hypnotics:
EvaluationHere are aspects of care that should be evaluated to determine effectiveness of drug therapy:
Barbiturates Used as Anxiolytic-Hypnotics
Therapeutic Action
Indications
Children
Adults
Older adults
PharmacokineticsRouteOnsetPeakDurationOral15 min30-60 min10-16 hIM, subcutaneous–10-30 min4-6 hIVUp 10 15 min5 min4-6 hT1/2: 79 hMetabolism: liver Excretion: urine Contraindications and Cautions
Adverse Effects
Interactions
Nursing ConsiderationsHere are important nursing considerations when administering this drug: Nursing AssessmentThese are the important things the nurse should include in conducting assessment, history taking, and examination:
Nursing DiagnosesHere are some of the nursing diagnoses that can be formulated in the use of this drug for therapy:
Implementation with RationaleThese are vital nursing interventions done in patients who are taking anxiolytic-hypnotics:
EvaluationHere are aspects of care that should be evaluated to determine effectiveness of drug therapy:
Practice Exam: Anxiolytic and Hypnotic DrugsQuestions to test your knowledge about anxiolytics and hypnotic drugs: Questions 1. What drug refers to the ability to help patient feel calm and unaware of his environment? A. Anesthesia 2. The most commonly used anxiolytics. A. Benzodiazepines ADVERTISEMENTS 3. Which of the following medical condition(s) can be considered as contraindication(s) to use of anxiolytics and hypnotics? A. Psychosis 4. What is the antidote of benzodiazepine? A. Theophylline 5. Abrupt withdrawal of barbiturates can precipitate what medical condition? A. Ascites 1. Answer: B. Sedatives. Hypnotic effect helps patients sleep and anxiolytic effect helps patients relieve feelings of tension and fear. 2. Answer: A. Benzodiazepines. They are the most commonly used anxiolytics because they can lyse or break the feeling of anxiety without causing much sedation and are less likely to make patients physically dependent. 3. Answer: D. Both A & B. Psychosis can be exacerbated by the sedative effect of the drug. On the other hand, alcoholic intoxication can be exacerbated by depressant effects of these drugs. Is respiratory distress a contraindication for the use of barbiturates?Contraindications: Barbiturate sensitivity, liver disease, impaired renal function, patients with severe respiratory distress, respiratory disease in which dyspnea, obstruction or cor pulmonale is present, acute or chronic pain.
Which condition is a contraindication for barbiturates?Barbiturates, including phenobarbital, are contraindicated in a patient with a history/manifest or latent porphyria, liver impairment, and large doses in patients with nephritic syndrome. Phenobarbital should not be given to persons with a known history of addiction to sedative-hypnotic medicines.
What is the most serious risk in the acute use of barbiturates?Death from overdose is the most significant risk associated with barbiturate use. Symptoms of an overdose can include: lack of coordination. slurred speech.
What is barbiturate used for?Barbiturates are a group of sedative-hypnotic medications used for the treatment of seizure disorder, neonatal withdrawal, insomnia, preoperative anxiety, and induction of coma for increased intracranial pressure. They are also useful for inducing anesthesia.
|